Typical scenario

A mixed DNA report leaves the donor count unexplained

If a report describes mixed DNA on an object's handle without explaining the assumed donor count, matching alleles may be mistaken for certain identification. Reviewing that reasoning requires raw data and calculation conditions, beyond the final match table.

What needs to be clarified

Review the documentary basis for the donor count and statistical evaluation, including alternative assumptions and the report's stated limitations.

Materials to prepare

  • Full report with locus tables and competing propositions
  • Electropherograms and available electronic data for the trace, controls and reference samples
  • Interpretation thresholds, model description and calculation settings

What to compare

Check tables against electropherograms, mixture components and possible allele drop-out or drop-in. Compare thresholds, controls and the donor-count rationale. Identify which propositions the likelihood ratio addresses and whether justified alternative conditions change the evaluation.

Possible outcome of the analysis

A review may list testable assumptions, gaps and calculation questions; sufficient data may permit an assessment of whether the mixture interpretation is reproducible.

Limits of the conclusions

Document review does not replace laboratory testing. Statistical support for a donor proposition alone cannot establish when or how DNA transferred or the circumstances of contact.